Raf Kinase Inhibitory Protein or RKIP was initially identified as a Raf-1 binding protein using the yeast 2-hybrid screen.RKIP inhibits the activation phosphorylation of MEK by Raf-1 by competitively inhibiting the binding of MEK to Raf-1 and thus exerting an inhibitory effect on the Raf-MEK-Erk pathway.RKIP has been identified as a metastasis supp
As a key technology to study the physical mechanism of single event effects (SEEs) and to identify the sensitive area of microelectronic devices, heavy ion micro-beam irradiation has been paid more and more attention by researchers.Single ion hit (SIH) is an important part of heavy ion micro-beam irradiation, which could reduce the number of incide
The development of new and improvement of existing methods for determining antioxidant activity is an urgent task of pharmacy, cosmetic and food industries.In the present work, the systematization and analysis of methods for determining antioxidant activity have been carried out, which have found the widest application and are described in the dome
Category: Ankle Arthritis; Arthroscopy; Trauma Introduction/Purpose: One of the options for the surgical treatment of tibial pilon fracture is the circular external fixator.Similar results are found in the literature, with good outcomes in relation to a low incidence of infection, osteomyelitis and soft tissue injuries compared to open reduction an